Analysis of predicted proteasomal cleavages in the methyltransferase domain from JEV

The methyltransferase (MTase, a 265 amino acid residues long region at the N-terminal end of the viral nonfunctional supermolecule NS5 domain) is key for viral replication in Japanese Encephalitis Virus (JEV). Sequence to structure to functional information with adequate knowledge on MTase from JEV...

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Veröffentlicht in:Bioinformation 2020-03, Vol.16 (3), p.223-228
Hauptverfasser: Afaq, Sarah, Malik, Arshi, Akhtar, Md Salman, Alwabli, Afaf S, Alzahrani, Dhafer A, Al-Solami, Habeeb M, Alzahrani, Othman, Alam, Qamre, Kamal, Mohammad Azhar, Abulfaraj, Aala A, Tarique, Mohammad
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Sprache:eng
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Zusammenfassung:The methyltransferase (MTase, a 265 amino acid residues long region at the N-terminal end of the viral nonfunctional supermolecule NS5 domain) is key for viral replication in Japanese Encephalitis Virus (JEV). Sequence to structure to functional information with adequate knowledge on MTase from JEV is currently limited. Therefore, it is of interest to document a report on the comprehensive analysis of predicted proteasomal cleavage data in the methyltransferase domain from JEV. This data is relevant in the design and development of vaccine and other therapeutic candidates for further consideration.
ISSN:0973-2063
0973-8894
0973-2063
DOI:10.6026/97320630016223