Abaloparatide at the Same Dose Has the Same Effects on Bone as PTH (1‐34) in Mice

ABSTRACT Abaloparatide, a novel analog of parathyroid hormone‐related protein (PTHrP 1–34), became in 2017 the second osteoanabolic therapy for the treatment of osteoporosis. This study aims to compare the effects of PTH (1‐34), PTHrP (1‐36), and abaloparatide on bone remodeling in male mice. Interm...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of bone and mineral research 2020-04, Vol.35 (4), p.714-724
Hauptverfasser:	Le Henaff, Carole, Ricarte, Florante, Finnie, Brandon, He, Zhiming, Johnson, Joshua, Warshaw, Johanna, Kolupaeva, Victoria, Partridge, Nicola C
Format:	Artikel
Sprache:	eng
Schlagworte:	ABALOPARATIDE BONE Bone growth Bone histomorphometry Bone marrow Bone mineral density Bone remodeling Bone resorption Bone turnover Cancellous bone Cbfa-1 protein Collagen Collagen (type I) Cortical bone Dual energy X-ray absorptiometry Femur Gene expression OSTEOANABOLICS Osteoblastogenesis Osteoblasts Osteogenesis OSTEOPOROSIS Parathyroid Parathyroid hormone Parathyroid hormone-related protein PTH SOST protein Tibia TRANCE protein Vitamin D
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!