Antibiotic antagonist: the curious career of René Dubos
Only rarely do historians mention another miracle drug, gramicidin, and the Rockefeller researcher who discovered it, René Dubos. To some extent this is understandable: despite being hailed in 1939 as a "hundred thousand times" more powerful than the sulpha drugs, gramicidin proved highly...
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Veröffentlicht in: | The Lancet (British edition) 2016-01, Vol.387 (10014), p.118-119 |
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Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Only rarely do historians mention another miracle drug, gramicidin, and the Rockefeller researcher who discovered it, René Dubos. To some extent this is understandable: despite being hailed in 1939 as a "hundred thousand times" more powerful than the sulpha drugs, gramicidin proved highly toxic when administered intravenously and although it was widely used during World War 2 to treat wounds and other topical infections it was soon eclipsed by streptomycin. |
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ISSN: | 0140-6736 1474-547X |
DOI: | 10.1016/S0140-6736(15)00840-5 |