Evolutionary selection of personalized melanoma cell/tissue dual-homing peptides for guiding bionanofibers to malignant tumors
Both melanoma cells and tissues were allowed to interact with an identical pool of billions of human-safe phage nanofiber clones with each genetically displaying a unique 12-mer peptide at the tips, respectively, resulting in the discovery of bionanofibers displaying a melanoma cell/tissue dual-homi...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2018-02, Vol.54 (13), p.1631-1634 |
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| container_issue | 13 |
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| container_title | Chemical communications (Cambridge, England) |
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| creator | Yang, Mingying Li, Yan Huai, Yanyan Wang, Chenyuan Yi, Wenfang Mao, Chuanbin |
| description | Both melanoma cells and tissues were allowed to interact with an identical pool of billions of human-safe phage nanofiber clones with each genetically displaying a unique 12-mer peptide at the tips, respectively, resulting in the discovery of bionanofibers displaying a melanoma cell/tissue dual-homing peptide for personalized targeted melanoma therapy. |
| doi_str_mv | 10.1039/c7cc09077c |
| format | Article |
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chemistry</subject><subject>Bacteriophage M13 - metabolism</subject><subject>Cell Line, Tumor</subject><subject>Chlorophyll - analogs & derivatives</subject><subject>Chlorophyll - therapeutic use</subject><subject>Drug Carriers - chemistry</subject><subject>Drug Carriers - metabolism</subject><subject>Drug Carriers - pharmacology</subject><subject>Female</subject><subject>Homing</subject><subject>Humans</subject><subject>Light</subject><subject>Melanocytes - metabolism</subject><subject>Melanoma</subject><subject>Melanoma - metabolism</subject><subject>Melanoma - therapy</subject><subject>Mice, Inbred BALB C</subject><subject>Nanofibers</subject><subject>Nanofibers - chemistry</subject><subject>Peptide Library</subject><subject>Peptides</subject><subject>Peptides - chemistry</subject><subject>Peptides - metabolism</subject><subject>Peptides - pharmacology</subject><subject>Phages</subject><subject>Photochemotherapy - methods</subject><subject>Photosensitizing Agents - therapeutic use</subject><subject>Protein Binding</subject><subject>Tips</subject><subject>Viral Proteins - 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| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2018-02, Vol.54 (13), p.1631-1634 |
| issn | 1359-7345 1364-548X 1364-548X |
| language | eng |
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| source | MEDLINE; Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
| subjects | Amino Acid Sequence Animals Bacteriophage M13 - chemistry Bacteriophage M13 - metabolism Cell Line, Tumor Chlorophyll - analogs & derivatives Chlorophyll - therapeutic use Drug Carriers - chemistry Drug Carriers - metabolism Drug Carriers - pharmacology Female Homing Humans Light Melanocytes - metabolism Melanoma Melanoma - metabolism Melanoma - therapy Mice, Inbred BALB C Nanofibers Nanofibers - chemistry Peptide Library Peptides Peptides - chemistry Peptides - metabolism Peptides - pharmacology Phages Photochemotherapy - methods Photosensitizing Agents - therapeutic use Protein Binding Tips Viral Proteins - chemistry Viral Proteins - metabolism Viral Proteins - pharmacology |
| title | Evolutionary selection of personalized melanoma cell/tissue dual-homing peptides for guiding bionanofibers to malignant tumors |
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