From Prior Information to Saccade Selection: Evolution of Frontal Eye Field Activity during Natural Scene Search

Abstract Prior knowledge about our environment influences our actions. How does this knowledge evolve into a final action plan and how does the brain represent this? Here, we investigated this question in the monkey oculomotor system during self-guided search of natural scenes. In the frontal eye fi...

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Veröffentlicht in:Cerebral cortex (New York, N.Y. 1991) N.Y. 1991), 2020-03, Vol.30 (3), p.1957-1973
Hauptverfasser: Glaser, Joshua I, Wood, Daniel K, Lawlor, Patrick N, Segraves, Mark A, Kording, Konrad P
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container_end_page 1973
container_issue 3
container_start_page 1957
container_title Cerebral cortex (New York, N.Y. 1991)
container_volume 30
creator Glaser, Joshua I
Wood, Daniel K
Lawlor, Patrick N
Segraves, Mark A
Kording, Konrad P
description Abstract Prior knowledge about our environment influences our actions. How does this knowledge evolve into a final action plan and how does the brain represent this? Here, we investigated this question in the monkey oculomotor system during self-guided search of natural scenes. In the frontal eye field (FEF), we found a subset of neurons, “Early neurons,” that contain information about the upcoming saccade long before it is executed, often before the previous saccade had even ended. Crucially, much of this early information did not relate to the actual saccade that would eventually be selected. Rather, it related to prior information about the probabilities of possible upcoming saccades based on the presaccade fixation location. Nearer to the time of saccade onset, a greater proportion of these neurons’ activities related to the saccade selection, although prior information continued to influence activity throughout. A separate subset of FEF neurons, “Late neurons,” only represented the final action plan near saccade onset and not prior information. Our results demonstrate how, across the population of FEF neurons, prior information evolves into definitive saccade plans.
doi_str_mv 10.1093/cercor/bhz216
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source Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Action Potentials - physiology
Animals
Attention - physiology
Fixation, Ocular - physiology
Frontal Lobe - physiology
Memory - physiology
Neurons - physiology
Original
Photic Stimulation - methods
Reaction Time - physiology
Visual Fields - physiology
Visual Perception - physiology
title From Prior Information to Saccade Selection: Evolution of Frontal Eye Field Activity during Natural Scene Search
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