Combination Antihypertensive Therapy Prescribing and Blood Pressure Control in a Real-World Setting

Combination Antihypertensive Therapy Prescribing and Blood Pressure Control in a Real-World Setting

Abstract BACKGROUND Specific combinations of two drug classes are recommended in a variety of clinical situations in the management of hypertension. These preferred combinations are based on complimentary blood pressure (BP) lowering mechanisms or benefit for a concomitant disease. METHODS Using ele...

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Veröffentlicht in:American journal of hypertension 2020-04, Vol.33 (4), p.316-324
Hauptverfasser: Magvanjav, Oyunbileg, Cooper-Dehoff, Rhonda M, McDonough, Caitrin W, Gong, Yan, Hogan, William R, Johnson, Julie A
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Antihypertensive Agents - therapeutic use
Blood Pressure - drug effects
Drug Prescriptions
Drug Therapy, Combination
Drug Utilization - trends
Electronic Health Records
Female
Humans
Hypertension - diagnosis
Hypertension - drug therapy
Hypertension - physiopathology
Male
Middle Aged
Original Contributions
Practice Patterns, Physicians' - trends
Treatment Outcome
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Zusammenfassung:Abstract BACKGROUND Specific combinations of two drug classes are recommended in a variety of clinical situations in the management of hypertension. These preferred combinations are based on complimentary blood pressure (BP) lowering mechanisms or benefit for a concomitant disease. METHODS Using electronic health records (EHRs) data from 27,579 ambulatory hypertensive patients, we investigated antihypertensive therapy prescribing patterns and associations of preferred two drug classes with BP control. RESULTS Overall, BP control, defined as BP
ISSN:0895-7061
1941-7225
DOI:10.1093/ajh/hpz196