Rapid Antigen Tests for Diagnosis of Pandemic (Swine) Influenza A/H1N1

We found that the sensitivities of 3 rapid influenza antigen tests for pandemic influenza A/H1N1 virus were low to moderate: BD Directigen EZ Flu A+B test (Becton Dickinson), 46.7%; BinaxNOW Influenza A&B (Inverness Medical), 38.3%; and QuickVue Influenza A+B Test (Quidel), 53.3%. A patient with...

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Veröffentlicht in:	Clinical infectious diseases 2009-10, Vol.49 (7), p.1090-1093
Hauptverfasser:	Vasoo, Shawn, Stevens, Jane, Singh, Kamaljit
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antigens Antigens, Viral - isolation & purification Biological and medical sciences BRIEF REPORTS Child Child, Preschool Diagnostic tests Diseases Emergency departments H1N1 subtype influenza A virus Human viral diseases Humans Immunoassay - methods Infant Infectious diseases Influenza Influenza A virus Influenza A Virus, H1N1 Subtype - isolation & purification Influenza, Human - diagnosis Influenza, Human - virology Medical diagnosis Medical sciences Middle Aged Pandemics Polymerase chain reaction Reagent Kits, Diagnostic Reverse transcriptase polymerase chain reaction Sensitivity and Specificity Specimens Swine flu Viral diseases Viral diseases of the respiratory system and ent viral diseases Viruses Young Adult
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Zusammenfassung:	We found that the sensitivities of 3 rapid influenza antigen tests for pandemic influenza A/H1N1 virus were low to moderate: BD Directigen EZ Flu A+B test (Becton Dickinson), 46.7%; BinaxNOW Influenza A&B (Inverness Medical), 38.3%; and QuickVue Influenza A+B Test (Quidel), 53.3%. A patient with influenza-like illness who has a negative rapid antigen test result should undergo further testing using reverse-transcription polymerase chain reaction.
ISSN:	1058-4838 1537-6591
DOI:	10.1086/644743