World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19)

An unprecedented outbreak of pneumonia of unknown aetiology in Wuhan City, Hubei province in China emerged in December 2019. A novel coronavirus was identified as the causative agent and was subsequently termed COVID-19 by the World Health Organization (WHO). Considered a relative of severe acute re...

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Veröffentlicht in:International journal of surgery (London, England) England), 2020-04, Vol.76, p.71-76
Hauptverfasser: Sohrabi, Catrin, Alsafi, Zaid, O'Neill, Niamh, Khan, Mehdi, Kerwan, Ahmed, Al-Jabir, Ahmed, Iosifidis, Christos, Agha, Riaz
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Sprache:eng
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Zusammenfassung:An unprecedented outbreak of pneumonia of unknown aetiology in Wuhan City, Hubei province in China emerged in December 2019. A novel coronavirus was identified as the causative agent and was subsequently termed COVID-19 by the World Health Organization (WHO). Considered a relative of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), COVID-19 is caused by a betacoronavirus named SARS-CoV-2 that affects the lower respiratory tract and manifests as pneumonia in humans. Despite rigorous global containment and quarantine efforts, the incidence of COVID-19 continues to rise, with 90,870 laboratory-confirmed cases and over 3,000 deaths worldwide. In response to this global outbreak, we summarise the current state of knowledge surrounding COVID-19. •COVID-19 outbreak has been declared a global health emergency.•COVID-19 has infected over 85,403 people worldwide, significantly more than SARS.•Clinical features of COVID-19 include fever, cough and dyspnoea.•Exact pathophysiological mechanisms are still unknown due to absent animal models.•Various countries have issued travel restrictions, contradicting the WHO's advice.
ISSN:1743-9191
1743-9159
DOI:10.1016/j.ijsu.2020.02.034