Reply to “The Connection between Celiac Disease and Hepatic Steatosis: High Levels of Pigment Epithelium-Derived Factor”

In addition to an increased inflammatory load in the intestinal wall, increased intestinal permeability and autoantibodies related to CD are the most suspected pathogenic mechanisms for liver diseases in CD, including hepatic steatosis [4]. [...]toxins, cytokines, and other unidentified molecules originating from the intestine can reach the liver for further liver damage. Muhammet Yener Akpinara, Evrim Kahramanoglu Aksoya, Ferdane Pirincci Sapmaza, Ozlem Ceylan Doganb, Metin Uzmana, Yasar Nazligula aDepartment of Gastroenterology, Kecioren Training and Research Hospital, Ankara, Turkey bDepartment of Medical Biochemistry, Ankara University Medical Faculty, Ankara, Turkey 1 Dikker O, Dağ H. The connection between celiac disease and hepatic steatosis: high levels of pigment epithelium-derived factor.