Oncological and functional outcomes of open versus laparoscopic partial nephrectomy in T1b tumors: A single-center analysis

This study aims to evaluate the oncological and functional results of open partial nephrectomy (OPN) and laparoscopic partial nephrectomy (LPN) at the T1b clinical stage, which constitutes 25% of renal cell carcinomas (RCC) at diagnosis. The characteristics of 63 patients with stage T1b solitary tum...

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Veröffentlicht in:International Brazilian Journal of Urology 2020-05, Vol.46 (3), p.341-350
Hauptverfasser: Kartal, Ibrahim, Karakoyunlu, Nihat, Çakici, Mehmet Çağlar, Karabacak, Osman, Sağnak, Levent, Ersoy, Hamit
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Sprache:eng
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Zusammenfassung:This study aims to evaluate the oncological and functional results of open partial nephrectomy (OPN) and laparoscopic partial nephrectomy (LPN) at the T1b clinical stage, which constitutes 25% of renal cell carcinomas (RCC) at diagnosis. The characteristics of 63 patients with stage T1b solitary tumor who underwent OPN (41) or LPN (22) were compared. The survival analysis was performed using the Kaplan-Meier method. Univariate and multivariate Cox regression analyses were performed to determine the factors affecting disease-free survival. Potential predictive factors, which might affect the postoperative glomerular filtration rate (GFR), were evaluated using multivariate linear regression analysis. No differences were observed between OPN and LPN groups regarding patient and tumor characteristics. Although the warm ischemia time, intraoperative estimated blood loss, and operation duration were higher in the LPN group, no differences were noted between the two techniques regarding complication rates (p
ISSN:1677-5538
1677-6119
DOI:10.1590/S1677-5538.IBJU.2018.0865