Counteracting Radio-Resistance Using the Optimization of Radiotherapy

Radiobiology research into tumor radioresistance has thus focused on targeting these mechanisms to increase radiotherapy effectiveness by, e.g., hypoxia modification, combination therapy with DNA damage repair and growth hormone inhibitors, or radio-enhancement components, such as metallic nanoparticles. [...]the population is largely exposed through all the conventional routes of contamination: ingestion, inhalation and skin. In their molecular and cellular study, Anakura and coworkers [3] compared the radiosensitivity to X-rays of several lung cancer cell lines according to the EGFR mutational status.