Incidence of frontotemporal disorders in Olmsted County: A population-based study
Frontotemporal dementia disorders (FTDs) are heterogeneous phenotypical behavioral and language disorders usually associated with frontal and/or temporal lobe degeneration. We investigated their incidence in a population-based cohort. Using a records-linkage system, we identified all patients with a...
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Veröffentlicht in: | Alzheimer's & dementia 2020-03, Vol.16 (3), p.482-490 |
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Sprache: | eng |
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Zusammenfassung: | Frontotemporal dementia disorders (FTDs) are heterogeneous phenotypical behavioral and language disorders usually associated with frontal and/or temporal lobe degeneration. We investigated their incidence in a population-based cohort.
Using a records-linkage system, we identified all patients with a diagnostic code for dementia in Olmsted County, MN, 1995–2010, and confirmed the diagnosis of FTD. A behavioral neurologist verified the clinical diagnosis and determined phenotypes.
We identified 35 FTD cases. Overall, the incidence of FTDs was 4.3/100,000/year (95% CI: 2.9, 5.7). Incidence was higher in men (6.3/100,000, 95% CI 3.6, 9.0) than women (2.9/100,000; 95% CI: 1.3, 4.5); we observed an increased trend over time (B = 0.83, 95% CI: 0.54, 1.11, P |
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ISSN: | 1552-5260 1552-5279 1552-5279 |
DOI: | 10.1016/j.jalz.2019.08.199 |