Drug Screen Identifies Leflunomide for Treatment of Inflammatory Bowel Diseases Caused by TTC7A Deficiency
In a screen of drugs, leflunomide was identified as an agent that might be used to treat patients with intestinal defects caused by mutations in the TTC7A gene.
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| Veröffentlicht in: | Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2019-11, Vol.158 (4), p.1000-1015 |
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| Sprache: | eng |
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| container_end_page | 1015 |
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| container_issue | 4 |
| container_start_page | 1000 |
| container_title | Gastroenterology (New York, N.Y. 1943) |
| container_volume | 158 |
| creator | Jardine, Sasha Anderson, Sierra Babcock, Stephen Leung, Gabriella Pan, Jie Dhingani, Neel Warner, Neil Guo, Conghui Siddiqui, Iram Kotlarz, Daniel Dowling, James J Melnyk, Roman Snapper, Scott B Klein, Christoph Thiagarajah, Jay R Muise, Aleixo M |
| description | In a screen of drugs, leflunomide was identified as an agent that might be used to treat patients with intestinal defects caused by mutations in the TTC7A gene. |
| doi_str_mv | 10.1053/j.gastro.2019.11.019 |
| format | Article |
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| identifier | ISSN: 0016-5085 |
| ispartof | Gastroenterology (New York, N.Y. 1943), 2019-11, Vol.158 (4), p.1000-1015 |
| issn | 0016-5085 1528-0012 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7062591 |
| source | Elsevier ScienceDirect Journals; Alma/SFX Local Collection |
| title | Drug Screen Identifies Leflunomide for Treatment of Inflammatory Bowel Diseases Caused by TTC7A Deficiency |
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