Prolonged outbreak of New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE), Tuscany, Italy, 2018 to 2019

In Tuscany, Italy, New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE) have increased since November 2018. Between November 2018 and October 2019, 1,645 samples were NDM-CRE-positive: 1,270 (77.2%) cases of intestinal carriage, 129 (7.8%) bloodstream infections...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Euro surveillance : bulletin européen sur les maladies transmissibles 2020-02, Vol.25 (6), p.1
Hauptverfasser:	Tavoschi, Lara, Forni, Silvia, Porretta, Andrea, Righi, Lorenzo, Pieralli, Filippo, Menichetti, Francesco, Falcone, Marco, Gemignani, Giulia, Sani, Spartaco, Vivani, Paola, Bellandi, Tommaso, Tacconi, Danilo, Turini, Lucia, Toccafondi, Giulio, Privitera, Gaetano, Lopalco, Pierluigi, Baggiani, Angelo, Gemmi, Fabrizio, Luchini, Grazia, Petrillo, Maurizio, Roti, Lorenzo, Pezzotti, Patrizio, Pantosti, Annalisa, Iannazzo, Stefania, Mechi, Maria Teresa, Rossolini, Gian Maria, On Behalf Of The Tuscan Clinical Microbiology Laboratory Network
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Anti-Bacterial Agents - pharmacology Antibiotics beta-Lactamases - drug effects beta-Lactamases - genetics beta-Lactamases - metabolism Carbapenems - pharmacology Child Child, Preschool CRE bacteria Disease control Disease Outbreaks Drug Resistance, Multiple, Bacterial - drug effects Epidemics Female Humans Infant Infant, Newborn Infectious diseases Italy - epidemiology Klebsiella Infections - drug therapy Klebsiella Infections - epidemiology Klebsiella Infections - microbiology Klebsiella pneumoniae - drug effects Klebsiella pneumoniae - enzymology Klebsiella pneumoniae - metabolism Male Microbial Sensitivity Tests Middle Aged Rapid Communication Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	In Tuscany, Italy, New Delhi metallo-beta-lactamase-producing carbapenem-resistant Enterobacterales (NDM-CRE) have increased since November 2018. Between November 2018 and October 2019, 1,645 samples were NDM-CRE-positive: 1,270 (77.2%) cases of intestinal carriage, 129 (7.8%) bloodstream infections and 246 (14.9%) infections/colonisations at other sites. were prevalent (1,495; 90.9%), with ST147/NDM-1 the dominant clone. Delayed outbreak identification and response resulted in sustained NDM-CRE transmission in the North-West area of Tuscany, but successfully contained spread within the region.
ISSN:	1560-7917 1025-496X 1560-7917
DOI:	10.2807/1560-7917.ES.2020.25.6.2000085