Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides

Highly Enantioselective Hiyama Cross-Coupling via Rh-Catalyzed Allylic Arylation of Racemic Allyl Chlorides

Highly enantioselective Hiyama cross-coupling reactions have been achieved through rhodium­(I)-catalyzed dynamic kinetic asymmetric transformations between aryl siloxanes and cyclic racemic allyl halides. This process affords valuable enantiomerically enriched aryl-substituted cyclic allyl products...

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Veröffentlicht in:Organometallics 2019-10, Vol.38 (20), p.3991-3995
Hauptverfasser: González, Jesús, Schäfer, Philipp, Fletcher, Stephen P
Format: Artikel
Sprache:eng
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Zusammenfassung:Highly enantioselective Hiyama cross-coupling reactions have been achieved through rhodium­(I)-catalyzed dynamic kinetic asymmetric transformations between aryl siloxanes and cyclic racemic allyl halides. This process affords valuable enantiomerically enriched aryl-substituted cyclic allyl products and is compatible with heterocyclic allyl chloride electrophiles.
ISSN:0276-7333
1520-6041
DOI:10.1021/acs.organomet.9b00197