Genetic manipulation of the pigment pathway in a sea urchin reveals distinct lineage commitment prior to metamorphosis in the bilateral to radial body plan transition

Echinoderms display a vast array of pigmentation and patterning in larval and adult life stages. This coloration is thought to be important for immune defense and camouflage. However, neither the cellular nor molecular mechanism that regulates this complex coloration in the adult is known. Here we k...

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Veröffentlicht in:	Scientific reports 2020-02, Vol.10 (1), p.1973-1973, Article 1973
Hauptverfasser:	Wessel, Gary M., Kiyomoto, Masato, Shen, Tun-Li, Yajima, Mamiko
Format:	Artikel
Sprache:	eng
Schlagworte:	631/136 631/181 631/337 631/45 631/601 631/80 Adults Albinism Animals Biosynthetic Pathways - genetics Body Patterning - physiology Camouflage Cell Lineage Coelomocytes Coloration CRISPR-Cas Systems - genetics Dimethylaniline monooxygenase (N-oxide-forming) Embryo, Nonmammalian Embryos Fertilization Flavin Gene Expression Regulation, Developmental Gene Knockout Techniques Genes Glial cells Humanities and Social Sciences Immune system Larvae Larval development Metamorphosis Metamorphosis, Biological multidisciplinary Oxygenases - genetics Oxygenases - metabolism Pigmentation Pigmentation - physiology Pigments Pigments, Biological - biosynthesis Polyketide synthase Polyketide Synthases - genetics Polyketide Synthases - metabolism Polyketides - metabolism Science Science (multidisciplinary) Sea Urchins - growth & development Stem cell transplantation Stem cells Transcription Factors - genetics Transcription Factors - metabolism
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