Evaluation of capsular contracture following immediate prepectoral versus subpectoral direct-to-implant breast reconstruction

Capsular contracture is a common adverse outcome following implant breast reconstruction, often associated with radiation treatment. The authors hypothesize that muscle fibrosis is the main contributor of breast reconstruction contracture after radiation. Retrospective chart review identified patien...

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Veröffentlicht in:Scientific reports 2020-01, Vol.10 (1), p.1137-1137, Article 1137
Hauptverfasser: Sobti, Nikhil, Weitzman, Rachel E., Nealon, Kassandra P., Jimenez, Rachel B., Gfrerer, Lisa, Mattos, David, Ehrlichman, Richard J., Gadd, Michele, Specht, Michelle, Austen, William G., Liao, Eric C.
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Sprache:eng
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Zusammenfassung:Capsular contracture is a common adverse outcome following implant breast reconstruction, often associated with radiation treatment. The authors hypothesize that muscle fibrosis is the main contributor of breast reconstruction contracture after radiation. Retrospective chart review identified patients that underwent DTI reconstruction with pre-or post-operative breast irradiation. Signs of capsular contracture were assessed using clinic notes and independent graders reviewing two-dimensional images and anatomic landmarks. Capsular contracture rate was greater in the subpectoral vs. prepectoral group (n = 28, 51.8% vs. n = 12, 30.0%, p = 0.02). When compared to prepectoral DTI reconstruction in irradiated patients, subpectoral implant placement was nearly 4 times as likely to result in capsular contracture (p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-58094-4