Antidiabetic activity of standardized dried tubers extract of Aconitum napellus in streptozotocin‐induced diabetic rats

India has got rich cultural inheritage in the forms of Ayurveda texts which are a rich and ample source of herbs, shrubs, trees and affluent in medicinally active phytoconstituents. Aconitum napellus is used for the cure of many ailments including rheumatoid arthritis, sciatica and gout. The present...

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Veröffentlicht in:3 Biotech 2020-02, Vol.10 (2), p.56-56, Article 56
Hauptverfasser: Shoaib, Ambreen, Salem-Bekhit, Mounir M., Siddiqui, Hefazat H., Dixit, Rakesh K., Bayomi, Mohsen, Khalid, Mohammad, Badruddeen, Shakeel, Faiyaz
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Sprache:eng
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Zusammenfassung:India has got rich cultural inheritage in the forms of Ayurveda texts which are a rich and ample source of herbs, shrubs, trees and affluent in medicinally active phytoconstituents. Aconitum napellus is used for the cure of many ailments including rheumatoid arthritis, sciatica and gout. The present work attempts to evaluate the physicochemical and preliminary phytochemical studies on the tubers of Aconitum napellus along with its antidiabetic activity. The herbal standardization was carried out on the basis of organoleptic properties, physical characteristics and physicochemical properties. The body weight of ACON-I (1.25 mg/kg) and ACON-II (2.5 mg/kg) was recorded as 190.40 and 209.40 g, respectively, compared with 163.00 g in diabetic rats at day 28. The body weight of ACON-I and ACON-II was significantly increased compared with diabetic rats ( p  
ISSN:2190-572X
2190-5738
DOI:10.1007/s13205-019-2043-7