Correlation between blood flow on optic nerve head and structural and functional changes in eyes with glaucoma

The purpose of this study was to determine the significance of the correlations between blood flow on the optic nerve head (ONH) using the mean blur rate (MBR) determined by laser speckle flowgraphy and the visual field loss determined by perimetry and the structural alterations by optical coherence...

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Veröffentlicht in:	Scientific reports 2020-01, Vol.10 (1), p.729-729, Article 729
Hauptverfasser:	Kuroda, Fumi, Iwase, Takeshi, Yamamoto, Kentaro, Ra, Eimei, Terasaki, Hiroko
Format:	Artikel
Sprache:	eng
Schlagworte:	692/308/409 692/700/1421 Aged Aged, 80 and over Blood flow Female Glaucoma Glaucoma, Open-Angle - diagnosis Glaucoma, Open-Angle - pathology Glaucoma, Open-Angle - physiopathology Humanities and Social Sciences Humans Male Middle Aged multidisciplinary Nerve Fibers - pathology Optic nerve Optic Nerve - blood supply Optic Nerve - pathology Optic Nerve - physiopathology Regional Blood Flow Regression analysis Retina Risk factors Science Science (multidisciplinary) Structure-function relationships Tissues Tomography, Optical Coherence Variance analysis Visual field Visual Field Tests Visual Fields
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Zusammenfassung:	The purpose of this study was to determine the significance of the correlations between blood flow on the optic nerve head (ONH) using the mean blur rate (MBR) determined by laser speckle flowgraphy and the visual field loss determined by perimetry and the structural alterations by optical coherence tomography in eyes solely with open-angle glaucoma. There were significant differences in the circumpapillary retinal nerve fiber layer thickness (cpRNFLT), and the MBR-tissue, at the different stages of glaucoma (ANOVA, P
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-020-57583-w