The expressions of YAP1, β-catenin and survivin in colon cancer tissues and their clinical significance
We aimed to evaluate the effects of YAP1, β-catenin, and survivin on the onset and progression of colon cancer, and to explore their correlations. The expressions of YAP1, β-catenin, and survivin in 106 colon cancer tissues and 55 normal colon mucosa tissues were measured by immunohistochemical assa...
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| Veröffentlicht in: | International journal of clinical and experimental pathology 2018-01, Vol.11 (12), p.6032-6038 |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
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| Zusammenfassung: | We aimed to evaluate the effects of YAP1, β-catenin, and survivin on the onset and progression of colon cancer, and to explore their correlations. The expressions of YAP1, β-catenin, and survivin in 106 colon cancer tissues and 55 normal colon mucosa tissues were measured by immunohistochemical assay. The correlations between their expressions and clinical and pathological characteristics were analyzed. The expression rates of YAP1, β-catenin, and survivin in colon cancer tissues were significantly higher than those in normal colon mucosa tissues (P0.05), but with the degree of differentiation, depth of invasion, lymph node metastasis and Duke's stage (P |
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| ISSN: | 1936-2625 |