Elevated Coefficient of Variation in Total Fecal Bile Acids Precedes Diagnosis of Necrotizing Enterocolitis

Accumulation of bile acids (BAs) may mediate development of necrotizing enterocolitis (NEC). Serial fecal samples were collected from premature infants with birth weight (BW) ≤ 1800 g, estimated gestational age (EGA) ≤ 32 weeks, and

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Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2020-01, Vol.10 (1), p.249-249, Article 249
Hauptverfasser:	Knapp, Shannon, Kehring, Allysa, Stepp, Jennifer, Calton, Christine M., Gephart, Sheila M., Bandlamuri, Sruti, Boyle, Kate E., Dietz, Grey I., Johnson, Haeley, Romo, Ryan E., Spencer, Mackenzie, Bedrick, Alan D., Halpern, Melissa D.
Format:	Artikel
Sprache:	eng
Schlagworte:	101/58 692/4020/1503/1581/3189 692/53/2423 Acids Bile Bile acids Bile Acids and Salts - chemistry Bile Acids and Salts - metabolism Birth weight Coefficient of variation Diagnosis Enteral feeding Enteral nutrition Enterocolitis Enterocolitis, Necrotizing - diagnosis Enterocolitis, Necrotizing - metabolism Feces Feces - chemistry Female Gastrointestinal diseases Gestational age Humanities and Social Sciences Humans Infant Infants Male multidisciplinary Necrosis Necrotizing enterocolitis Science Science (multidisciplinary) Statistical analysis Variation
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Beschreibung
Zusammenfassung:	Accumulation of bile acids (BAs) may mediate development of necrotizing enterocolitis (NEC). Serial fecal samples were collected from premature infants with birth weight (BW) ≤ 1800 g, estimated gestational age (EGA) ≤ 32 weeks, and
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-019-57178-0