A lack of consideration of a dose–response relationship can lead to erroneous conclusions regarding 100% fruit juice and the risk of cardiometabolic disease

The question remains as to whether there is any evidence demonstrating an association between 100% fruit juice and cardiometabolic disease that is similar to that found with SSBs. Seeking a simple binary answer of harm or benefit would be overly simplistic as it disregards the complex relationships that exists between various foods, their nutrient matrix and disease. We propose that the evidence needed to assess if 100% fruit juices are similar to SSBs require us to understand the population level dose–response relationships.