Evaluation of the potential of the Ki67 index to predict tumor evolution in patients with pituitary adenoma

Evaluation of the potential of the Ki67 index to predict tumor evolution in patients with pituitary adenoma

The aggressive course of a number of pituitary adenomas requires the investigation of potential predictors. This study aimed to investigate the proliferation marker Ki67 as a predictor of postoperative outcome in patients with pituitary adenoma regarding recurrence and regrowth of the tumor, using a...

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Veröffentlicht in:International journal of clinical and experimental pathology 2019, Vol.12 (1), p.320-326
Hauptverfasser: Petry, Carolina, Poli, Jefferson Henrique Zwir, de Azevedo Dossin, Isabella, Rech, Carolina Garcia Soares Leães, Pereira Lima, Júlia Fernanda Semmelmann, Ferreira, Nelson Pires, da Costa Oliveira, Miriam
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Sprache:eng
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Zusammenfassung:The aggressive course of a number of pituitary adenomas requires the investigation of potential predictors. This study aimed to investigate the proliferation marker Ki67 as a predictor of postoperative outcome in patients with pituitary adenoma regarding recurrence and regrowth of the tumor, using a Ki67 cut-off value of 3%. This retrospective study included 52 patients with pituitary adenoma who had undergone adenomectomy and had a pituitary image taken at least 1 year after surgery. Patients were divided according to Ki67 expression into high (≥3%) vs. low (
ISSN:1936-2625