Step by step Indiana pouch construction in a previously irradiated patient with a cervical cancer relapse

•Radical pelvic surgery is the golden standard surgical treatment of pelvic malignances and urinary diversion is often needed.•Catheterizable continent urinary derivation (CCUD) is one of the best options in young patients.•Indiana Pouch is a reproductible technique with low rate of complications. Radiation therapy and radical pelvic surgery, either radical cystectomy or pelvic exenteration, is the golden standard treatment for infiltrating bladder carcinoma, as well as advanced or recurrent cervical, vulvar, vaginal and endometrial cancer. However, due to the poor radiation sensitivity of the cervix and vagina, a high-radiation dose is required, leading to early and/or late onset urogenital complications in approximately 50% of the patients. The following case report describes a 64-year-old native Russian woman presenting a relapse of a vaginal cuff squamous cell carcinoma, who underwent a laterally extended endopelvic resection (LEER) followed by a neobladder reconstruction based on the Indiana pouch (IP) technique. The process is described here step by step. Indiana pouch urinary diversion was based on thorough research, the reproducibility of the technique, our urologist’s experience with the Indiana Pouch, as well the lower rate of complications published in various separate series. Indiana pouch is a successful continence urinary reservoir with a reproductible technique, however long-term observation is needed.