Association between localised retinal nerve fibre layer defects and cardiovascular risk factors

Association between localised retinal nerve fibre layer defects and cardiovascular risk factors

Localised retinal nerve fibre layer defects (RNFLDs) are reported to indicate the degree of glaucomatous damage but can also be sequelae of retinal vascular insufficiency as a result of systemic vascular factors. We investigated the association between RNFLDs and cardiovascular risk factors. RNFLDs...

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Veröffentlicht in:Scientific reports 2019-12, Vol.9 (1), p.19340-7, Article 19340
Hauptverfasser: Shin, Joo Youn, Lee, Jonghyun, Lee, Chan Joo, Park, Sungha, Byeon, Suk Ho
Format: Artikel
Sprache:eng
Schlagworte:
692/1807/1482
692/699/3161/3172
Adult
Aged
Atherosclerosis - pathology
Blood pressure
Cardiovascular diseases
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - pathology
Female
Health risk assessment
Health risks
Humanities and Social Sciences
Humans
Logistic Models
Male
Middle Aged
multidisciplinary
Multivariate Analysis
Nerve Fibers - pathology
Retina
Retina - diagnostic imaging
Retina - pathology
Risk Factors
Science
Science (multidisciplinary)
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Zusammenfassung:Localised retinal nerve fibre layer defects (RNFLDs) are reported to indicate the degree of glaucomatous damage but can also be sequelae of retinal vascular insufficiency as a result of systemic vascular factors. We investigated the association between RNFLDs and cardiovascular risk factors. RNFLDs were detected in 440 (29.2%) of 1508 subjects. The presence of RNFLDs was associated with higher HbA 1c (odds ratio [OR] 1.289, p  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-019-55846-9