A Talented Duo: IFIT1 and IFIT3 Patrol Viral RNA Caps
Hosts respond to viral infection by expressing interferon-stimulated genes, of which IFITs are potent inhibitors of viral RNA translation. Johnson et al. (2018) solved the structure of the IFIT1-IFIT3 complex bound cap 0 RNA and explored their concerted antiviral activity. Hosts respond to viral inf...
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| Veröffentlicht in: | Immunity (Cambridge, Mass.) Mass.), 2018-03, Vol.48 (3), p.474-476 |
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| container_end_page | 476 |
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| container_title | Immunity (Cambridge, Mass.) |
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| creator | Choi, Youn Jung Bowman, James W. Jung, Jae U. |
| description | Hosts respond to viral infection by expressing interferon-stimulated genes, of which IFITs are potent inhibitors of viral RNA translation. Johnson et al. (2018) solved the structure of the IFIT1-IFIT3 complex bound cap 0 RNA and explored their concerted antiviral activity.
Hosts respond to viral infection by expressing interferon-stimulated genes, of which IFITs are potent inhibitors of viral RNA translation. Johnson et al. (2018) solved the structure of the IFIT1-IFIT3 complex bound cap 0 RNA and explored their concerted antiviral activity. |
| doi_str_mv | 10.1016/j.immuni.2018.03.001 |
| format | Article |
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Hosts respond to viral infection by expressing interferon-stimulated genes, of which IFITs are potent inhibitors of viral RNA translation. Johnson et al. 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| ispartof | Immunity (Cambridge, Mass.), 2018-03, Vol.48 (3), p.474-476 |
| issn | 1074-7613 1097-4180 |
| language | eng |
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| source | MEDLINE; Cell Press Free Archives; Access via ScienceDirect (Elsevier); EZB-FREE-00999 freely available EZB journals |
| subjects | Antiviral activity Carrier Proteins - genetics Cryopyrin-Associated Periodic Syndromes Detonators Humans Infections Interferon Intracellular Signaling Peptides and Proteins Protein Biosynthesis Proteins Ribonucleic acid RNA RNA Caps RNA, Viral Viral infections Viruses West Nile virus |
| title | A Talented Duo: IFIT1 and IFIT3 Patrol Viral RNA Caps |
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