Parechovirus A Pathogenesis and the Enigma of Genotype A-3

Parechovirus A Pathogenesis and the Enigma of Genotype A-3

is a species in the genus within the family that can cause severe disease in children. Relatively little is known on epidemiology and pathogenesis. This review aims to explore the literature and highlight the differences between genotypes from a pathogenesis standpoint. In particular, the curious ca...

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Veröffentlicht in:Viruses 2019-11, Vol.11 (11), p.1062
Hauptverfasser: Sridhar, Adithya, Karelehto, Eveliina, Brouwer, Lieke, Pajkrt, Dasja, Wolthers, Katja C
Format: Artikel
Sprache:eng
Schlagworte:
children
disease severity
Epidemiology
Evolution
Genomes
genotype
Genotype & phenotype
Genotypes
Infections
Mutation
Parechovirus
Pathogenesis
Proteins
Review
RNA polymerase
Sepsis
Viral infections
Viruses
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Beschreibung
Zusammenfassung:is a species in the genus within the family that can cause severe disease in children. Relatively little is known on epidemiology and pathogenesis. This review aims to explore the literature and highlight the differences between genotypes from a pathogenesis standpoint. In particular, the curious case of Parechovirus-A3 and the genotype-specific disease association will be discussed. Finally, a brief outlook on research is provided.
ISSN:1999-4915
1999-4915
DOI:10.3390/v11111062