Experience with non-vitamin K antagonists in the Netherlands: stories from both sides of the desk
[...]this lack of monitoring may come with new challenges and downsides, namely more inappropriate dosing and non-adherence [6]. [...]non-adherence to anticoagulants is likely to result in inappropriately low drug levels, and consequently, the cessation of the effect that they are intended for in th...
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| Veröffentlicht in: | Netherlands heart journal 2019-12, Vol.27 (12), p.587-589 |
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| container_title | Netherlands heart journal |
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| creator | de Vries, T. A. C. de Groot, J. R. |
| description | [...]this lack of monitoring may come with new challenges and downsides, namely more inappropriate dosing and non-adherence [6]. [...]non-adherence to anticoagulants is likely to result in inappropriately low drug levels, and consequently, the cessation of the effect that they are intended for in the first place: to prevent thromboembolic complications [5, 6]. [...]the NOAC and VKA groups were not derived from the same population: users of VKAs were solely from a centre focussing on diagnostics located in Rotterdam, whereas the NOAC group was derived from a secondary/tertiary care hospital located in Nieuwegein [7]. [...]due to the differences in their offset of action and mechanism of producing an anticoagulant effect it’s unlikely that the reported non-adherence to both types of anticoagulants directly translates into a similarly reduced efficacy. |
| doi_str_mv | 10.1007/s12471-019-01346-4 |
| format | Article |
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| ispartof | Netherlands heart journal, 2019-12, Vol.27 (12), p.587-589 |
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| source | PubMed Central Free; Springer Nature OA Free Journals; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Anticoagulants Cardiac arrhythmia Cardiology Clinical medicine Cohort analysis Drug dosages Editor's Comment Heart Medical Education Medicine Medicine & Public Health Patients Self report Stroke Thromboembolism Thrombosis |
| title | Experience with non-vitamin K antagonists in the Netherlands: stories from both sides of the desk |
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