Altered functional connectivity in early Alzheimer's disease: A resting-state fMRI study

Previous studies have led to the proposal that patients with Alzheimer's disease (AD) may have disturbed functional connectivity between different brain regions. Furthermore, recent resting‐state functional magnetic resonance imaging (fMRI) studies have also shown that low‐frequency (

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Bibliographische Detailangaben
Veröffentlicht in:	Human brain mapping 2007-10, Vol.28 (10), p.967-978
Hauptverfasser:	Wang, Kun, Liang, Meng, Wang, Liang, Tian, Lixia, Zhang, Xinqing, Li, Kuncheng, Jiang, Tianzi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alzheimer Disease - diagnosis Alzheimer Disease - physiopathology Alzheimer's disease Biological and medical sciences Brain - anatomy & histology Brain - physiopathology Cognition Disorders - diagnosis Cognition Disorders - physiopathology Computer Science Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Disease Progression Early Diagnosis Electrodiagnosis. Electric activity recording Female fMRI functional connectivity Functional Laterality - physiology Humans Image Processing, Computer-Assisted Investigative techniques, diagnostic techniques (general aspects) low-frequency blood oxygenation level-dependent fluctuations Magnetic Resonance Imaging - methods Male Medical Imaging Medical sciences Middle Aged Nerve Net - anatomy & histology Nerve Net - physiopathology Nervous system Neural Pathways - anatomy & histology Neural Pathways - physiopathology Neurology Neuropsychological Tests Occipital Lobe - anatomy & histology Occipital Lobe - physiopathology Parietal Lobe - anatomy & histology Parietal Lobe - physiopathology Predictive Value of Tests Prefrontal Cortex - anatomy & histology Prefrontal Cortex - physiopathology Prognosis Radiodiagnosis. Nmr imagery. Nmr spectrometry resting-state
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Beschreibung
Zusammenfassung:	Previous studies have led to the proposal that patients with Alzheimer's disease (AD) may have disturbed functional connectivity between different brain regions. Furthermore, recent resting‐state functional magnetic resonance imaging (fMRI) studies have also shown that low‐frequency (
ISSN:	1065-9471 1097-0193
DOI:	10.1002/hbm.20324