Anatomical correlates for category-specific naming of objects and actions: A brain stimulation mapping study

The production of object and action words can be dissociated in aphasics, yet their anatomical correlates have been difficult to distinguish in functional imaging studies. To investigate the extent to which the cortical neural networks underlying object‐ and action‐naming processing overlap, we perf...

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Veröffentlicht in:Human brain mapping 2014-02, Vol.35 (2), p.429-443
Hauptverfasser: Lubrano, Vincent, Filleron, Thomas, Démonet, Jean-François, Roux, Franck-Emmanuel
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Sprache:eng
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Zusammenfassung:The production of object and action words can be dissociated in aphasics, yet their anatomical correlates have been difficult to distinguish in functional imaging studies. To investigate the extent to which the cortical neural networks underlying object‐ and action‐naming processing overlap, we performed electrostimulation mapping (ESM), which is a neurosurgical mapping technique routinely used to examine language function during brain‐tumor resections. Forty‐one right‐handed patients who had surgery for a brain tumor were asked to perform overt naming of object and action pictures under stimulation. Overall, 73 out of the 633 stimulated cortical sites (11.5%) were associated with stimulation‐induced language interferences. These interference sites were very much localized (
ISSN:1065-9471
1097-0193
DOI:10.1002/hbm.22189