Pluripotent Cell Models for Gonadal Research

Sex development is a complex process involving many genes and hormones. Defects in this process lead to Differences of Sex Development (DSD), a group of heterogeneous conditions not as rare as previously thought. Part of the obstacles in proper management of these patients is due to an incomplete un...

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Veröffentlicht in:	International journal of molecular sciences 2019-11, Vol.20 (21), p.5495
Hauptverfasser:	Rodríguez Gutiérrez, Daniel, Biason-Lauber, Anna
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell culture Cellular Reprogramming Techniques - methods Disorders of Sex Development - metabolism Disorders of Sex Development - pathology Disorders of Sex Development - therapy Females Gonads - cytology Gonads - growth & development Gonads - metabolism Humans In vitro fertilization Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism Males Mutation Ovaries Patient-Specific Modeling Patients Pluripotency Primary Cell Culture - methods Proteins Review Stem cells Testes Tumors
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