Heritable variation at the chromosome 21 gene ERG is associated with acute lymphoblastic leukemia risk in children with and without Down syndrome

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Veröffentlicht in:	Leukemia 2019-11, Vol.33 (11), p.2746-2751
Hauptverfasser:	de Smith, Adam J., Walsh, Kyle M., Morimoto, Libby M., Francis, Stephen S., Hansen, Helen M., Jeon, Soyoung, Gonseth, Semira, Chen, Minhui, Sun, Hanxiao, Luna-Fineman, Sandra, Antillón, Federico, Girón, Verónica, Kang, Alice Y., Smirnov, Ivan, Shao, Xiaorong, Whitehead, Todd P., Barcellos, Lisa F., Jolly, Kent W., Healy, Jasmine, Laverdière, Caroline, Sinnett, Daniel, Taub, Jeffrey W., Birch, Jillian M., Thompson, Pamela D., Pombo-de-Oliveira, Maria S., Spector, Logan G., DeWan, Andrew T., Mueller, Beth A., Chiang, Charleston, Metayer, Catherine, Ma, Xiaomei, Wiemels, Joseph L.
Format:	Artikel
Sprache:	eng
Schlagworte:	45/43 45/61 45/77 631/208 631/67/1990/283/2125 631/67/2324 692/699/1541/1990/283/2125 Acute lymphoblastic leukemia Acute lymphocytic leukemia Adolescent California - epidemiology California - ethnology Cancer Research Case-Control Studies Child Child, Preschool Children Chromosome 21 Chromosomes Chromosomes, Human, Pair 21 - genetics Critical Care Medicine Down syndrome Down Syndrome - complications Down Syndrome - ethnology Down Syndrome - genetics Down's syndrome Female Genetic aspects Genetic Predisposition to Disease Genome-Wide Association Study Guatemala - epidemiology Guatemala - ethnology Haplotypes Health aspects Hematology Hispanic or Latino Humans Infant Infant, Newborn Intensive Internal Medicine Letter Leukemia Lymphatic leukemia Male Medicine Medicine & Public Health Oncology Polymorphism, Single Nucleotide Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications Precursor Cell Lymphoblastic Leukemia-Lymphoma - ethnology Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics Principal Component Analysis Risk Factors Transcriptional Regulator ERG - genetics
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ISSN:	0887-6924 1476-5551 1476-5551
DOI:	10.1038/s41375-019-0514-9