Target highlights in CASP13: Experimental target structures through the eyes of their authors

The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submi...

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Veröffentlicht in:	Proteins, structure, function, and bioinformatics structure, function, and bioinformatics, 2019-12, Vol.87 (12), p.1037-1057
Hauptverfasser:	Lepore, Rosalba, Kryshtafovych, Andriy, Alahuhta, Markus, Veraszto, Harshul A., Bomble, Yannick J., Bufton, Joshua C., Bullock, Alex N., Caba, Cody, Cao, Hongnan, Davies, Owen R., Desfosses, Ambroise, Dunne, Matthew, Fidelis, Krzysztof, Goulding, Celia W., Gurusaran, Manickam, Gutsche, Irina, Harding, Christopher J., Hartmann, Marcus D., Hayes, Christopher S., Joachimiak, Andrzej, Leiman, Petr G., Loppnau, Peter, Lovering, Andrew L., Lunin, Vladimir V., Michalska, Karolina, Mir‐Sanchis, Ignacio, Mitra, AK, Moult, John, Phillips Jr, George N., Pinkas, Daniel M., Rice, Phoebe A., Tong, Yufeng, Topf, Maya, Walton, Jonathan D., Schwede, Torsten
Format:	Artikel
Sprache:	eng
Schlagworte:	Arabidopsis - chemistry Arabidopsis - ultrastructure Bacterial Proteins - chemistry Bacterial Proteins - ultrastructure BASIC BIOLOGICAL SCIENCES Biochemistry, Molecular Biology CASP Casp Experiment Overview CASP, protein structure prediction Computational Biology cryo-EM Crystallography, X-Ray Humans Life Sciences Models, Molecular Protein Conformation protein structure prediction Proteins - chemistry Proteins - genetics Proteins - ultrastructure Structural Biology X-ray crystallography
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Zusammenfassung:	The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment.
ISSN:	0887-3585 1097-0134
DOI:	10.1002/prot.25805