Histone Deacetylase 7 Inhibition in a Murine Model of Gram-Negative Pneumonia-Induced Acute Lung Injury

BACKGROUND:Pulmonary infections remain the most common cause of Acute Respiratory Distress Syndrome (ARDS), a pulmonary inflammatory disease with high mortality, for which no targeted therapy currently exists. We have previously demonstrated an ameliorated syndrome with early, broad spectrum Histone...

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Veröffentlicht in:Shock (Augusta, Ga.) Ga.), 2020-03, Vol.53 (3), p.344-351
Hauptverfasser: Kasotakis, George, Kintsurashvili, Ekaterina, Galvan, Manuel D., Graham, Christopher, Purves, J. Todd, Agarwal, Suresh, Corcoran, David L., Sullenger, Bruce A., Palmer, Scott M., Remick, Daniel G.
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Sprache:eng
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