Effect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery: The FIBRES Randomized Clinical Trial

Effect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery: The FIBRES Randomized Clinical Trial

IMPORTANCE: Excessive bleeding is a common complication of cardiac surgery. An important cause of bleeding is acquired hypofibrinogenemia (fibrinogen level

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Veröffentlicht in:JAMA : the journal of the American Medical Association 2019-11, Vol.322 (20), p.1966-1976
Hauptverfasser: Callum, Jeannie, Farkouh, Michael E, Scales, Damon C, Heddle, Nancy M, Crowther, Mark, Rao, Vivek, Hucke, Hans-Peter, Carroll, Jo, Grewal, Deep, Brar, Sukhpal, Bussières, Jean, Grocott, Hilary, Harle, Christopher, Pavenski, Katerina, Rochon, Antoine, Saha, Tarit, Shepherd, Lois, Syed, Summer, Tran, Diem, Wong, Daniel, Zeller, Michelle, Karkouti, Keyvan
Format: Artikel
Sprache:eng
Schlagworte:
Bleeding
Blood transfusion
Bypasses
Clinical significance
Clinical trials
Erythrocytes
Fibrinogen
Health risk assessment
Heart
Heart surgery
Online First
Original Investigation
Patients
Platelets
Surgery
Thromboembolism
Transfusion
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Zusammenfassung:IMPORTANCE: Excessive bleeding is a common complication of cardiac surgery. An important cause of bleeding is acquired hypofibrinogenemia (fibrinogen level
ISSN:0098-7484
1538-3598
DOI:10.1001/jama.2019.17312