Trimethylamine-N-Oxide (TMAO) Predicts Cardiovascular Mortality in Peripheral Artery Disease

Peripheral artery disease (PAD) is a major cause of acute and chronic illness, with extremely poor prognosis that remains underdiagnosed and undertreated. Trimethylamine-N-Oxide (TMAO), a gut derived metabolite, has been associated with atherosclerotic burden. We determined plasma levels of TMAO by...

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Veröffentlicht in:	Scientific reports 2019-10, Vol.9 (1), p.15580-8, Article 15580
Hauptverfasser:	Roncal, Carmen, Martínez-Aguilar, Esther, Orbe, Josune, Ravassa, Susana, Fernandez-Montero, Alejandro, Saenz-Pipaon, Goren, Ugarte, Ana, Estella-Hermoso de Mendoza, Ander, Rodriguez, Jose A., Fernández-Alonso, Sebastián, Fernández-Alonso, Leopoldo, Oyarzabal, Julen, Paramo, Jose A.
Format:	Artikel
Sprache:	eng
Schlagworte:	692/308/409 692/499 692/53/2422 82 82/58 Aged Arteriosclerosis Cardiovascular diseases Digestive system Dimethylaniline monooxygenase (N-oxide-forming) Female Gastrointestinal tract Health risks Humanities and Social Sciences Humans Intestine Ischemia Male Mass spectrometry Mass spectroscopy Metabolites Methylamines - metabolism Mortality multidisciplinary Oxidation Peripheral Arterial Disease - diagnosis Peripheral Arterial Disease - metabolism Peripheral Arterial Disease - mortality Plasma levels Prognosis Renal function Risk Assessment Science Science (multidisciplinary) Trimethylamine Trimethylamine-N-oxide Vascular diseases
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