Neurotuberculosis: Control of Steroid-Refractory Paradoxical Inflammatory Reaction With Ruxolitinib
Paradoxical inflammatory reactions associated with treatment of neurotuberculosis can lead to severe morbidity and mortality and may not be controlled by steroids alone. We report the use of the Janus kinase inhibitor ruxolitinib to treat a steroid-refractory neurotuberculosis paradoxical reaction.
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| Veröffentlicht in: | Open Forum Infectious Diseases 2019-10, Vol.6 (10), p.ofz422-ofz422 |
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| container_issue | 10 |
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| container_title | Open Forum Infectious Diseases |
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| creator | Xie, Yingda L Ita-Nagy, Fanny Chen, Ray Y Manion, Maura M Sereti, Irini Pei, Luxin Holland, Steven M |
| description | Paradoxical inflammatory reactions associated with treatment of neurotuberculosis can lead to severe morbidity and mortality and may not be controlled by steroids alone. We report the use of the Janus kinase inhibitor ruxolitinib to treat a steroid-refractory neurotuberculosis paradoxical reaction. |
| doi_str_mv | 10.1093/ofid/ofz422 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 2328-8957 |
| ispartof | Open Forum Infectious Diseases, 2019-10, Vol.6 (10), p.ofz422-ofz422 |
| issn | 2328-8957 2328-8957 |
| language | eng |
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| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Oxford Journals Open Access Collection; PubMed Central |
| subjects | Adverse and side effects Brief Report Care and treatment Drugs Editor's Choice Tuberculosis |
| title | Neurotuberculosis: Control of Steroid-Refractory Paradoxical Inflammatory Reaction With Ruxolitinib |
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