High HDL-C levels reduce the risk of obstructive coronary artery disease in asymptomatic diabetics who achieved optimal glycemic control

High HDL-C levels reduce the risk of obstructive coronary artery disease in asymptomatic diabetics who achieved optimal glycemic control

The benefit of a high level of high-density lipoprotein cholesterol (HDL-C) against coronary atherosclerosis risk after achieving optimal glycemic control (OGC) in diabetics remains uncertain. We aimed to evaluate the association between HDL-C and obstructive coronary artery disease (CAD) according...

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Veröffentlicht in:Scientific reports 2019-10, Vol.9 (1), p.15306-7, Article 15306
Hauptverfasser: Park, Gyung-Min, Lee, Yongjik, Won, Ki-Bum, Yang, Yu Jin, Park, Sangwoo, Ann, Soe Hee, Kim, Yong-Giun, Yang, Dong Hyun, Kang, Joon-Won, Lim, Tae-Hwan, Kim, Hong-Kyu, Choe, Jaewon, Lee, Seung-Whan, Kim, Young-Hak, Kim, Shin-Jae, Lee, Sang-Gon
Format: Artikel
Sprache:eng
Schlagworte:
692/163/2743/137/138
692/4019/592/75/593/1353
Angiography
Arteriosclerosis
Blood Glucose - metabolism
Cardiovascular disease
Cholesterol
Cholesterol, HDL - blood
Computed tomography
Coronary artery
Coronary Artery Disease - blood
Coronary Artery Disease - epidemiology
Coronary vessels
Diabetes Mellitus - blood
Female
Health risk assessment
Heart diseases
Hemoglobin
High density lipoprotein
Humanities and Social Sciences
Humans
Male
Middle Aged
multidisciplinary
Plaques
Prevalence
Regression analysis
Risk Factors
Science
Science (multidisciplinary)
Stenosis
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Zusammenfassung:The benefit of a high level of high-density lipoprotein cholesterol (HDL-C) against coronary atherosclerosis risk after achieving optimal glycemic control (OGC) in diabetics remains uncertain. We aimed to evaluate the association between HDL-C and obstructive coronary artery disease (CAD) according to OGC status in diabetics. We analyzed 1,114 asymptomatic diabetics who underwent coronary computed tomographic angiography in a health examination. OGC was defined as hemoglobin A1C
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-019-51732-6