Impaired thiol/disulfide homeostasis in patients with mild acute pancreatitis

Impaired thiol/disulfide homeostasis in patients with mild acute pancreatitis

The aim of this study was to compare the dynamic thiol/disulfide (SS) homeostasis and ischemia-modified albumin (IMA) concentration between healthy subjects and patients with mild acute pancreatitis (AP). A total of 28 patients with AP (AP group) and 35 age- and sex-matched healthy individuals (cont...

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Veröffentlicht in:The Turkish journal of gastroenterology 2019-10, Vol.30 (10), p.899-902
Hauptverfasser: Uyanıkoğlu, Ahmet, Sabuncu, Tevfik, Yıldız, Rukiye, Cindioğlu, Çiğdem, Kirmit, Adnan, Erel, Özcan
Format: Artikel
Sprache:eng
Schlagworte:
Acute Disease
Adult
Aged
Aged, 80 and over
Albumin
Biomarkers - blood
Case-Control Studies
Comparative analysis
Disulfides - blood
Female
Homeostasis
Humans
Ischemia
Male
Medical schools
Middle Aged
Original
Pancreatitis
Pancreatitis - blood
Serum Albumin, Human
Sulfhydryl Compounds - blood
Thiols
Young Adult
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Zusammenfassung:The aim of this study was to compare the dynamic thiol/disulfide (SS) homeostasis and ischemia-modified albumin (IMA) concentration between healthy subjects and patients with mild acute pancreatitis (AP). A total of 28 patients with AP (AP group) and 35 age- and sex-matched healthy individuals (control group) were included in this study. Serum thiols/SS and IMA concentrations were measured and compared between the two groups. The mean serum native thiol (SH) and total thiol (TT) levels were significantly lower in the AP group than in the control group (224.7±80.3 μmol/L vs. 314.66±87.5 μmol/L, p
ISSN:2148-5607
1300-4948
2148-5607
DOI:10.5152/tjg.2019.18775