Microsatellite instability in endometrial cancer: New purpose for an old test

Microsatellite instability in endometrial cancer: New purpose for an old test

Historically, microsatellite instability testing has been used to identify patients with endometrial cancer with Lynch syndrome. It currently is also being used to identify those individuals who may be candidates for immunotherapy.

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Bibliographische Detailangaben
Veröffentlicht in:Cancer 2019-07, Vol.125 (13), p.2154-2163
Hauptverfasser: Kurnit, Katherine C., Westin, Shannon N., Coleman, Robert L.
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers, Tumor - genetics
Cancer
Colorectal cancer
Endometrial cancer
Endometrial Neoplasms - diagnosis
Endometrial Neoplasms - drug therapy
Endometrial Neoplasms - genetics
Endometrium
Female
Genetic disorders
Historical account
Hormone replacement therapy
Humans
Immunotherapy
Immunotherapy - methods
Lynch syndrome
Microsatellite Instability
mismatch repair deficiency
Oncology
Prognosis
Stability
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Beschreibung
Zusammenfassung:Historically, microsatellite instability testing has been used to identify patients with endometrial cancer with Lynch syndrome. It currently is also being used to identify those individuals who may be candidates for immunotherapy.
ISSN:0008-543X
1097-0142
1097-0142
DOI:10.1002/cncr.32058