Antibiotic selection in the treatment of acute invasive infections by Pseudomonas aeruginosa

Pseudomonas aeruginosa is characterized by an important intrinsic resistance to antibiotics and it possess an extraordinary ability to develop resistance to nearly all available antimicrobials through selection of mutations. We review some of the pharmacodynamic principles of antibiotics predicting...

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Veröffentlicht in:	Revista española de quimioterapia 2019-09, Vol.32 Suppl 2 (Suppl 2), p.32-34
Hauptverfasser:	Cardozo, C, Rico, V, Agüero, D, Soriano, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Cross Infection - drug therapy Cross Infection - microbiology Drug Resistance, Bacterial - drug effects Drug Resistance, Bacterial - genetics Humans Microbial Sensitivity Tests Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - genetics Pseudomonas Infections - drug therapy Pseudomonas Infections - microbiology Update in Nosocomial Infection
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Zusammenfassung:	Pseudomonas aeruginosa is characterized by an important intrinsic resistance to antibiotics and it possess an extraordinary ability to develop resistance to nearly all available antimicrobials through selection of mutations. We review some of the pharmacodynamic principles of antibiotics predicting efficacy, clinical experience with monotherapy and combination therapy, and principles for antibiotic treatment for empirical and directed treatment of P. aeruginosa invasive infections.
ISSN:	0214-3429 1988-9518