A study of contact lens compliance in a non-clinical setting

•Daily replacement wearers were more compliant with lens replacement, but all replacement types had similar compliance with overnight wear.•Contact lens wearers who are non-compliant with prescribed contact lens replacement are more likely to be non-compliant with overnight wear.•Contact lens case replacement was not associated with lens replacement or overnight wear compliance.•Eye care providers should provide clear compliance education – especially on overnight wear and case replacement - when prescribing contact lenses. To evaluate soft contact lens replacement, overnight (ON) wear, and contact lens case compliance in a non-clinical sample. Subjects (n = 297) were recruited at the Center for Science and Industry (COSI) in Columbus, Ohio. Adult (≥ 18 years) soft contact lens wearers completed a survey about contact lens replacement, ON contact lens wear, and contact lens case replacement habits. Two-week replacement lenses (according to the manufacturer’s replacement schedule [MRS]) were most common (45.5%), followed by monthly (34.3%) and daily replacement (20.2%). Non-compliance with replacement schedule was reported in 38.7% of subjects. Age (p = 0.02), years of lens wear (p = 0.02), and MRS (p