Recurrence patterns after resection of retroperitoneal sarcomas: An eight‐institution study from the US Sarcoma Collaborative

Background and Objectives Resection of primary retroperitoneal sarcomas (RPS) has a high incidence of recurrence. This study aims to identify patterns of recurrence and its impact on overall survival. Methods Adult patients with primary retroperitoneal soft tissue sarcomas who underwent resection in 2000‐2016 at eight institutions of the US Sarcoma Collaborative were evaluated. Results Four hundred and ninety‐eight patients were analyzed, with 56.2% (280 of 498) having recurrences. There were 433 recurrences (1‐8) in 280 patients with 126 (25.3%) being locoregional, 82 (16.5%) distant, and 72 (14.5%) both locoregional and distant. Multivariate analyses revealed the following: Patient age P = .0002), tumor grade (P = .02), local recurrence (P = .0003) and distant recurrence (P