Nickel-Catalyzed Oxidative Decarboxylative Annulation for the Synthesis of Heterocycle-Containing Phenanthridinones

A nickel-catalyzed oxidative decarboxylative annulation reaction of simple benzamides and (hetero)aromatic carboxylates has been developed. This reaction provides access to a large array of phenanthridinones and their heterocyclic analogues, highlighting the utility and versatility of oxidative dec...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Organic letters 2018-11, Vol.20 (22), p.7216-7219
Hauptverfasser:	Honeycutt, Aaron P, Hoover, Jessica M
Format:	Artikel
Sprache:	eng
Schlagworte:	benzamides Benzamides - chemistry Carboxylic Acids - chemistry Catalysis chemical bonding chemical reactions chemical structure heterocyclic compounds Heterocyclic Compounds, 3-Ring - chemical synthesis Heterocyclic Compounds, 3-Ring - chemistry Molecular Structure Nickel - chemistry Oxidation-Reduction Phenanthrenes - chemical synthesis Phenanthrenes - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A nickel-catalyzed oxidative decarboxylative annulation reaction of simple benzamides and (hetero)aromatic carboxylates has been developed. This reaction provides access to a large array of phenanthridinones and their heterocyclic analogues, highlighting the utility and versatility of oxidative decarboxylative coupling strategies for C–C bond formation.
ISSN:	1523-7060 1523-7052 1523-7052
DOI:	10.1021/acs.orglett.8b03144