Association Between Weight Loss Before Deceased Donor Kidney Transplantation and Posttransplantation Outcomes

There is debate on whether weight loss, a hallmark of frailty, signals higher risk for adverse outcomes among recipients of deceased donor kidney transplantation (DDKT). Retrospective cohort study. Using national Organ Procurement and Transplantation Network data, we included all DDKT recipients in...

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Veröffentlicht in:	American journal of kidney diseases 2019-09, Vol.74 (3), p.361-372
Hauptverfasser:	Harhay, Meera Nair, Ranganna, Karthik, Boyle, Suzanne M., Brown, Antonia M., Bajakian, Thalia, Levin Mizrahi, Lissa B., Xiao, Gary, Guy, Stephen, Malat, Gregory, Segev, Dorry L., Reich, David, McAdams-DeMarco, Mara
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Cadaver Cohort Studies deceased donor kidney transplantation (DDKT) end-stage kidney disease (ESKD) Female frailty graft failure Humans Kidney Transplantation Male Middle Aged mortality obesity outcomes Postoperative Complications - epidemiology Preoperative Period protein-wasting malnutrition Renal transplantation Retrospective Studies Risk Factors sarcopenia Tissue Donors Treatment Outcome wasting Weight Loss Young Adult
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Zusammenfassung:	There is debate on whether weight loss, a hallmark of frailty, signals higher risk for adverse outcomes among recipients of deceased donor kidney transplantation (DDKT). Retrospective cohort study. Using national Organ Procurement and Transplantation Network data, we included all DDKT recipients in the United States between December 4, 2004, and December 3, 2014, who were adults (aged ≥ 18 years) when listed for DDKT. Relative pre-DDKT weight change as a continuous predictor and categorized as
ISSN:	0272-6386 1523-6838
DOI:	10.1053/j.ajkd.2019.03.418