Cardiac magnetic resonance feature tracking for quantifying right ventricular deformation in type 2 diabetes mellitus patients

To determine the feasibility of deformation analysis in the right ventricle (RV) using cardiovascular magnetic resonance myocardial feature tracking (CMR-FT) in type 2 diabetes mellitus (T2DM) patients. We enrolled 104 T2DM patients, including 14 with impaired right ventricular ejection fraction (RV...

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Veröffentlicht in:Scientific reports 2019-07, Vol.9 (1), p.11148-11, Article 11148
Hauptverfasser: Hu, Bi-yue, Wang, Jin, Yang, Zhi-gang, Ren, Yan, Jiang, Li, Xie, Lin-jun, Liu, Xi, Gao, Yue, Shen, Meng-ting, Xu, Hua-yan, Shi, Ke, Li, Zhen-lin, Xia, Chun-chao, Peng, Wan-lin, Deng, Ming-yan, Li, Hong, Guo, Ying-kun
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Sprache:eng
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Zusammenfassung:To determine the feasibility of deformation analysis in the right ventricle (RV) using cardiovascular magnetic resonance myocardial feature tracking (CMR-FT) in type 2 diabetes mellitus (T2DM) patients. We enrolled 104 T2DM patients, including 14 with impaired right ventricular ejection fraction (RVEF) and 90 with preserved RVEF, and 26 healthy controls in this prospective study. CMR was used to determine RV feature-tracking parameters. RV strain parameters were compared among the controls, patients with preserved and reduced RVEF. Binary logistic regression was used to predict RV dysfunction. Receiver operating characteristic analysis was used to assess the diagnostic accuracy. The agreement was tested by Bland–Altman analysis. Compared with controls, longitudinal and circumferential global peak strain (PS) and PS at mid-ventricular, apical slices were significantly decreased in T2DM patients with or without reduced RVEF (p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-019-46755-y