Mouse T cells express a neurotransmitter-receptor signature that is quantitatively modulated in a subset- and activation-dependent manner

•Peripheral T cells transcribe less than 30 of the 185 annotated Neurotransmitter receptor genes.•More than half (14–16) of these NR transcripts are found in all subsets constituting a “core” signature.•We identify a narrow subset of

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Bibliographische Detailangaben
Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2019-08, Vol.80, p.275-285
Hauptverfasser:	Rosenberg, Kenneth M., Singh, Nevil J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Female Lymphocyte Activation Male Mice, Inbred C57BL Receptors, Neurotransmitter - genetics Receptors, Neurotransmitter - metabolism T-Lymphocyte Subsets - metabolism T-Lymphocytes - metabolism
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	•Peripheral T cells transcribe less than 30 of the 185 annotated Neurotransmitter receptor genes.•More than half (14–16) of these NR transcripts are found in all subsets constituting a “core” signature.•We identify a narrow subset of
ISSN:	0889-1591 1090-2139 1090-2139
DOI:	10.1016/j.bbi.2019.04.002