Safety and efficacy of pharmacological thromboprophylaxis for hospitalized patients with cirrhosis: a single‐center retrospective cohort study

Summary Background Hospitalized patients with cirrhosis are at increased risk for venous thromboembolism (VTE). The benefits and risks of pharmacological thromboprohylaxis in these patients have not been well studied. Objectives To examine the safety and efficacy of pharmacological VTE prophylaxis i...

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Veröffentlicht in:Journal of thrombosis and haemostasis 2015-07, Vol.13 (7), p.1245-1253
Hauptverfasser: Shatzel, J., Dulai, P. S., Harbin, D., Cheung, H., Reid, T. N., Kim, J., James, S. L., Khine, H., Batman, S., Whyman, J., Dickson, R. C., Ornstein, D. L.
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Sprache:eng
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Zusammenfassung:Summary Background Hospitalized patients with cirrhosis are at increased risk for venous thromboembolism (VTE). The benefits and risks of pharmacological thromboprohylaxis in these patients have not been well studied. Objectives To examine the safety and efficacy of pharmacological VTE prophylaxis in hospitalized cirrhotic patients. Patients/Methods Retrospective cohort study of patients with cirrhosis hospitalized at an academic tertiary care referral center over a 5‐year period. Results Six hundred hospital admissions accounting for 402 patients were included. VTE prophylaxis was administered during 296 (49%) admissions. Patients receiving VTE prophylaxis were older (59 years vs. 55 years, P 
ISSN:1538-7933
1538-7836
1538-7836
DOI:10.1111/jth.13000