Effect of hemodialysis on traditional and innovative cardiac markers

The diagnostic approach to acute coronary syndrome (ACS) is challenging in patients with impaired renal function since most serum biomarkers are commonly increased in this clinical setting. Cardiac troponin T (cTnT), creatine kinase isoenzyme MB (CK MB), myoglobin, and ischemia modified albumin (IMA...

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Veröffentlicht in:	Journal of clinical laboratory analysis 2008, Vol.22 (1), p.59-65
Hauptverfasser:	Montagnana, Martina, Lippi, Giuseppe, Tessitore, Nicola, Salvagno, Gian Luca, Targher, Giovanni, Gelati, Matteo, Lupo, Antonio, Guidi, Gian Cesare
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged albumin cobalt binding Biomarkers - blood cardiac laboratory markers Cardiovascular Diseases - blood chronic renal failure Creatine Kinase, MB Form - blood Diabetes Mellitus - blood Female hemodialysis Humans ischemia modified albumin Male Myocardial Ischemia - blood Myocardium - enzymology Myocardium - metabolism Myoglobin - blood Original Renal Dialysis Serum Albumin - analysis Troponin T - blood troponins
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Zusammenfassung:	The diagnostic approach to acute coronary syndrome (ACS) is challenging in patients with impaired renal function since most serum biomarkers are commonly increased in this clinical setting. Cardiac troponin T (cTnT), creatine kinase isoenzyme MB (CK MB), myoglobin, and ischemia modified albumin (IMA), were assayed in 45 patients prehemodialysis (pre‐HD) and posthemodialysis (post‐HD), and results were adjusted for hemoconcentration. The pre‐HD values of serum IMA and cTnT were above the respective diagnostic thresholds (IMA
ISSN:	0887-8013 1098-2825
DOI:	10.1002/jcla.20210