Prophylactic treatment of hyperbaric oxygen treatment mitigates inflammatory response via mitochondria transfer

Summary Aims Hyperbaric oxygen therapy (HBOT) has been widely used as postinjury treatment; however, we investigate its ability to mitigate potential damage as a preconditioning option. Here, we tested the hypothesis that HBOT preconditioning mitigates cell death in primary rat neuronal cells (PRNCs...

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Veröffentlicht in:	CNS neuroscience & therapeutics 2019-08, Vol.25 (8), p.815-823
Hauptverfasser:	Lippert, Trenton, Borlongan, Cesario V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Astrocytes Brain Injuries, Traumatic - therapy Cell death Cell Survival Cell viability Cells, Cultured hyperbaric Hyperbaric oxygen therapy Hyperbaric Oxygenation Inflammation Inflammation - therapy Lipopolysaccharides Mitochondria Mitochondria - physiology mitochondria transfer Original preconditioning Rats Rats, Sprague-Dawley Stroke Stroke - therapy Traumatic brain injury Tumor necrosis factor Tumor necrosis factor-TNF
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